| 2. | st 12.08.202012.08. | ŠKF ORION TIP SereďSER | 4:0 |  FK SenicaSEN | 16 | 0 | 0 | 50,0% | 66,7% | 9 | 0 |
| 3. | so 15.08.202015.08. | FK SenicaSEN | 3:0 |  MFK Zemplín MichalovceMIC | 79 | 0 | 0 | 35,3% | 54,8% | 31 | |
| 5. | so 29.08.202029.08. | FK SenicaSEN | 0:0 |  FC NitraNIT | 74 | 0 | 0 | 57,1% | 63,2% | 38 | 0 |
| 6. | pi 11.09.202011.09. | FC ViOn Zlaté Moravce - VrábleZMO | 2:2 | FK SenicaSEN | 58 | 0 | 1 | 38,9% | 62,5% | 16 | 0 |
| 7. | ne 20.09.202020.09. | FK SenicaSEN | 2:4 |  FC DAC 1904 Dunajská StredaDAC | 90 | 0 | 1 | 30,0% | 52,0% | 25 | 0 |
| 8. | so 26.09.202026.09. | FK SenicaSEN | 0:2 |  FC Spartak TrnavaSPA | 72 | 0 | 0 | 45,0% | 50,0% | 22 | 0 |
| 4. | st 30.09.202030.09. | ŠK Slovan Bratislava SLO | 2:0 | FK SenicaSEN | 15 | 0 | 0 | 0,0% | 80,0% | 5 | 0 |
| 9. | ne 04.10.202004.10. | AS TrenčínTRE | 0:1 | FK SenicaSEN | 78 | 0 | 0 | 41,2% | 68,2% | 22 | 0 |
| 11. | so 24.10.202024.10. | FK Pohronie Žiar n.H. Dolná ŽdaňaPOH | 1:2 | FK SenicaSEN | 1 | 0 | 0 | 0,0% | 0,0% | 0 | 0 |
| 12. | so 31.10.202031.10. | MŠK ŽilinaMŠK | 3:1 | FK SenicaSEN | 22 | 0 | 0 | 25,0% | 70,0% | 10 | 0 |
| 20. | so 20.02.202120.02. | MFK Zemplín MichalovceMIC | 0:2 | ŠKF ORION TIP SereďSER | 72 | 0 | 0 | 36,4% | 59,1% | 22 | 0 |
| 19. | ut 23.02.202123.02. | ŠKF ORION TIP SereďSER | 1:2 | FC NitraNIT | 71 | 0 | 0 | 23,8% | 66,7% | 12 | 0 |
| 21. | ne 28.02.202128.02. | ŠKF ORION TIP SereďSER | 0:5 | ŠK Slovan Bratislava SLO | 62 | 0 | 0 | 45,5% | 76,5% | 17 | |
| 22. | so 06.03.202106.03. | FC ViOn Zlaté Moravce - VrábleZMO | 1:0 | ŠKF ORION TIP SereďSER | 44 | 0 | 0 | 41,7% | 54,5% | 11 | 0 |
| - 3. | so 03.04.202103.04. | FK Pohronie Žiar n.H. Dolná ŽdaňaPOH | 1:2 | ŠKF ORION TIP SereďSER | 87 | 1 | 0 | 33,3% | 50,0% | 22 | 0 |
| - 4. | so 10.04.202110.04. | ŠKF ORION TIP SereďSER | 2:1 | FC NitraNIT | 46 | 0 | 0 | 35,7% | 81,8% | 11 | 0 |
| - 6. | so 24.04.202124.04. | MFK RužomberokRUŽ | 2:1 | ŠKF ORION TIP SereďSER | 28 | 0 | 0 | 14,3% | 66,7% | 3 | 0 |
